Publications

  • Drake, K., Lemoine, C., Aquino, G.S., Vaeth, A.M., and Kanadia, R.N., 2020. Loss of U11 small nuclear RNA in the developing mouse limb results in micromelia. Development, 147(21), dev.190967, [abstract]
  • Olthof, A.M., Rasmussen, J., Campeau, P.M., and Kanadia, R.N., 2020. Disrupted minor intron splicing is prevalent in Mendelian disorders. Molecular Genetics & Genomic Medicine, 8(9), mgg3.1374. [abstract]
  • Olthof, A.M., White, A. Lee, M.F., Chakroun, A. Abdelaleem, A.K., Rousseau, J., Magnani, C., Campeau, P.M., and Kanadia, R.N., 2020. The minor and major spliceosome interact to regulate alternative splicing around minor introns. 2020.05.18.101246. [abstract]
  • Drake, K., Lemoine, C., Aquino, G.S., Vaeth, A.M., and Kanadia, R.N., 2020. Minor spliceosome disruption causes limb growth defects without altering patterning. 2020.03.16.994384. [abstract]
  • Olthof, A.M., Hyatt, K.C., and Kanadia, R.N., 2019. Minor intron splicing revisited: identification of new minor intron-containing genes and tissue-dependent retention and alternative splicing of minor introns. BMC Genomics, 20(1), s128-019-6046-x. [abstract]
  • Baumgartner, M., Drake, K., and Kanadia, R.N., 2019. An Integrated Model of Minor Intron Emergence and Conservation. Frontiers in Genetics, 10(1113), fgene.2019.01113. [abstract] 
  • Baumgartner, M., Olthof, A.M., Aquino, G.S., Hyatt, K.C., Lemoine, C., Drake, K., Sturrock, N., Nguyen, N., Al Seesi, S., and Kanadia, R.N., 2018. Minor spliceosome inactivation causes microcephaly, owing to cell cycle defects and death of self-amplifying radial glial cells. Development145(17), p.dev166322.  [abstract]
  • Karunakaran, D.K.P. and Kanadia, R., 2017. In Vivo and Explant Electroporation of Morpholinos in the Developing Mouse Retina. In Morpholino Oligomers (pp. 215-227). Humana Press, New York, NY.  [abstract]
  • Karunakaran, D.K.P., Al Seesi, S., Banday, A.R., Baumgartner, M., Olthof, A., Lemoine, C., Măndoiu, I.I. and Kanadia, R.N., 2016. Network-based bioinformatics analysis of spatio-temporal RNA-Seq data reveals transcriptional programs underpinning normal and aberrant retinal development. BMC genomics17(5), p.495.  [abstract]
  • Karunakaran, D.K.P., Chhaya, N., Lemoine, C., Congdon, S., Black, A. and Kanadia, R., 2015. Loss of Citron kinase affects a subset of progenitor cells that alters late but not early neurogenesis in the developing rat retina. Investigative ophthalmology & visual science56(2), pp.787-798.  [abstract]
  • Baumgartner, M., Lemoine, C., Al Seesi, S., Karunakaran, D.K.P., Sturrock, N., Banday, A.R., Kilcollins, A.M., Mandoiu, I. and Kanadia, R.N., 2015. Minor splicing sn RNA s are enriched in the developing mouse CNS and are crucial for survival of differentiating retinal neurons. Developmental neurobiology75(9), pp.895-907.  [abstract]
  • Karunakaran, D.K.P., Congdon, S., Guerrette, T., Banday, A.R., Lemoine, C., Chhaya, N. and Kanadia, R., 2013. The expression analysis of Sfrs10 and Celf4 during mouse retinal development. Gene Expression Patterns13(8), pp.425-436.  [abstract]
  • Karunakaran, D.K.P., Banday, A.R., Wu, Q. and Kanadia, R., 2013. Expression analysis of an evolutionarily conserved alternative splicing factor, Sfrs10, in age-related macular degeneration. PloS one8(9), p.e75964.  [abstract]
  • Banday, A.R., Baumgartner, M., Al Seesi, S., Karunakaran, D.K.P., Venkatesh, A., Congdon, S., Lemoine, C., Kilcollins, A.M., Mandoiu, I., Punzo, C. and Kanadia, R.N., 2014. Replication-dependent histone genes are actively transcribed in differentiating and aging retinal neurons. Cell Cycle13(16), pp.2526-2541.  [abstract]
  • Mangul, S., Caciula, A., Al Seesi, S., Brinza, D., Banday, A.R. and Kanadia, R., 2012, October. An integer programming approach to novel transcript reconstruction from paired-end RNA-Seq reads. In Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine (pp. 369-376). ACM.  [abstract]
  • Mai-Anh Huynh, Yoshiho Ikeuchi, Stuart Netherton,  Luis de la Torre-Ubieta, Rahul N. Kanadia, Judith Stegmüller, Constance Cepko, Shirin Bonni, Azad Bonni 2011, An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain.  Neuron Volume 69, Issue 5, 930-944, 10 March 2011  [abstract]
  • Rahul N. Kanadia, Victoria E. Clark, Claudio Punzo, Jeffrey Trimarchi and Constance Cepko.  2008, Temporal requirement of the alternative splicing factor Sfrs1 for the survival of retinal neurons.  Development. Vol 135(23), 3923-33.  [abstract]
  • Rahul N. Kanadia, Jihae Shin, Yuan Yuan, Stuart G Beattie, Thurman Wheeler, Charles A Thornton and Maurice S. Swanson.  Reversal of RNA mis-splicing and myotonia following muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.  2006.  Proceedings of the National Academy of Sciences, USA.  August 1st; 103 (31):  11748-53  [abstract]
  • Rahul N Kanadia, Johnstone KA, Mankodi A, Lungu C, Thornton CA, Esson D, Timmers, Hauswirth WW, Swanson MS.  2003.  A muscleblind knockout model for myotonic dystrophy.  Science. 302(5652): 1978-80  [abstract]
  • Rahul N. Kanadia, Yuan Yuan, Michael G Poulos and Maurice Swanson.  2005.  Journal of Biomolecular Structure and Dynamics.  Book of Abstract Albany 2005 Vol 22, No. 6 June
  • Lin X, Miller JW, Mankodi A, Rahul N. Kanadia, Yuan Y, Moxley RT, Swanson MS, Thornton CA. 2006.  Failure of MBNL1-dependent postnatal splicing transitions in myotonic dystrophy. 2006. Human Molecular Genetics.  July 1st; 15 (13): 2087-97  [abstract]
  • Yuan Yuan, Rahul N Kanadia, Maurice S. Swanson.  2005.  Impact of Unstable Microsatellites on RNA processing (Review).  CHEMTRACTS Biochemistry and Molecular Biology.  18(3):  129-140
  • Rahul N Kanadia, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS.  2003.  Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.  Gene Expr Patterns. 3(4): 459-62.  [abstract]
  • Rahul N. Kanadia, Kuo WN, Mcnabb M, Botchway A.  1998.  Constitutive nitric oxide synthase in Saccharomyces cerevisiae.  Biochem Mol Biol Int. Sep; 45(6):1081-7.  [abstract]
  • Kuo WN, Rahul N. Kanadia, Shanbhag VP, Toro R.  1999.  Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart.  Mol Cell Biochem. 201(1-2): 11-6.  [abstract]
  • Kuo WN, Rahul N. Kanadia, Shanbhag VP, Morgan R.  1999.  Modification of proteins and polynucleotides by peroxynitrite.  Cytobios. 99(390): 47-55.  [abstract]
  • Kuo WN, Rahul N. Kanadia, Shanbhag VP.  1999.  Denitration of peroxynitrite-treated proteins by "protein nitratases" from dog prostate.  Biochem Mol Biol Int. Jun; 47(6):1061-7.  [abstract]
  • Kuo WN, Rahul N. Kanadia, Mcnabb M.  1998.  Soluble guanylate cyclase in Saccharomyces cerevisiae.  Biochem Mol Biol Int. Jun; 45(1):125-31. [abstract]
  • Kuo WN, McNabb M, Rahul N. Kanadia, Dopson N, Morgan R.  1997.  The presence/absence of Bcl-2, Ca2+/calmodulin-dependent protein kinase IV, calretinin and p53 in baker's yeast and wheat germ.  Cytobios. 91(364):7-13.  [abstract]
  • Kuo WN, Jn-Baptiste JB, Rahul N. Kanadia, McNabb LD, Zhai L, Weeks K, Dopson N, Chambers MC.  1996.  Immunoreactivities of m-calpain, calpastatin, nitric oxide synthase, myelin basic protein and dynamin II in baker's yeast, wheat germ and lobster tail muscle.  Cytobios. 87(351):251-63.  [abstract]